00000 - Document - Template Link link:presentationLink link:calculationLink link:definitionLink 100000 - Document - Document and Entity Information link:calculationLink link:presentationLink link:definitionLink 100010 - Statement - Consolidated Balance Sheets link:calculationLink link:presentationLink link:definitionLink 100020 - Statement - Consolidated Balance Sheets (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 100030 - Statement - Consolidated Statements of Operations and Comprehensive Loss link:calculationLink link:presentationLink link:definitionLink 100040 - Statement - Consolidated Statements of Stockholders' Equity link:calculationLink link:presentationLink link:definitionLink 100050 - Statement - Consolidated Statements of Stockholders' Equity (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 100060 - Statement - Consolidated Statements of Cash Flows link:calculationLink link:presentationLink link:definitionLink 100070 - Disclosure - Nature of Organization and Operations link:calculationLink link:presentationLink link:definitionLink 100080 - Disclosure - Summary of Significant Accounting Policies link:calculationLink link:presentationLink link:definitionLink 100090 - Disclosure - Accounts Payable and Accrued Expenses link:calculationLink link:presentationLink link:definitionLink 100100 - Disclosure - Furniture and Equipment link:calculationLink link:presentationLink link:definitionLink 100110 - Disclosure - Common Stock link:calculationLink link:presentationLink link:definitionLink 100120 - Disclosure - Preferred Stock link:calculationLink link:presentationLink link:definitionLink 100130 - Disclosure - Stock-Based Compensation link:calculationLink link:presentationLink link:definitionLink 100140 - Disclosure - Income Taxes link:calculationLink link:presentationLink link:definitionLink 100150 - Disclosure - Net and Comprehensive Loss Per Share Attributable to Common Stockholders link:calculationLink link:presentationLink link:definitionLink 100160 - Disclosure - Quarterly Results (Unaudited) link:calculationLink link:presentationLink link:definitionLink 100170 - Disclosure - Leases link:calculationLink link:presentationLink link:definitionLink 100180 - Disclosure - Employee Retirement Plan link:calculationLink link:presentationLink link:definitionLink 100190 - Disclosure - Employee Bonus Plan link:calculationLink link:presentationLink link:definitionLink 100200 - Disclosure - Employee Stock Purchase Plan link:calculationLink link:presentationLink link:definitionLink 100210 - Disclosure - License Agreement link:calculationLink link:presentationLink link:definitionLink 100220 - Disclosure - Restructuring link:calculationLink link:presentationLink link:definitionLink 100230 - Disclosure - Summary of Significant Accounting Policies (Policies) link:calculationLink link:presentationLink link:definitionLink 100240 - Disclosure - Summary of Significant Accounting Policies (Tables) link:calculationLink link:presentationLink link:definitionLink 100250 - Disclosure - Accounts Payable and Accrued Expenses (Tables) link:calculationLink link:presentationLink link:definitionLink 100260 - Disclosure - Furniture and Equipment (Tables) link:calculationLink link:presentationLink link:definitionLink 100270 - Disclosure - Stock-Based Compensation (Tables) link:calculationLink link:presentationLink link:definitionLink 100280 - Disclosure - Income Taxes (Tables) link:calculationLink link:presentationLink link:definitionLink 100290 - Disclosure - Net and Comprehensive Loss Per Share Attributable to Common Stockholders (Tables) link:calculationLink link:presentationLink link:definitionLink 100300 - Disclosure - Quarterly Results (Unaudited) (Tables) link:calculationLink link:presentationLink link:definitionLink 100310 - Disclosure - Leases (Tables) link:calculationLink link:presentationLink link:definitionLink 100320 - Disclosure - Nature of Organization and Operations - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100330 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100340 - Disclosure - Summary of Significant Accounting Policies - Schedule of Assets Measured on Recurring Basis (Detail) link:calculationLink link:presentationLink link:definitionLink 100350 - Disclosure - Accounts Payable and Accrued Expenses - Schedule of Accounts Payable and Accrued Expenses (Detail) link:calculationLink link:presentationLink link:definitionLink 100360 - Disclosure - Furniture and Equipment - Summary of Components of Furniture and Equipment (Detail) link:calculationLink link:presentationLink link:definitionLink 100370 - Disclosure - Common Stock - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100380 - Disclosure - Preferred Stock - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100390 - Disclosure - Stock-Based Compensation - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100400 - Disclosure - Stock-Based Compensation - Summary of Stock Option Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 100410 - Disclosure - Stock-Based Compensation - Stock Options Valuation Assumptions (Detail) link:calculationLink link:presentationLink link:definitionLink 100420 - Disclosure - Stock-Based Compensation - Summary of Restricted Stock Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 100430 - Disclosure - Stock-Based Compensation - Summary of Recognized Compensation Cost Related to Employee and Non-employee Stock-Based Compensation Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 100440 - Disclosure - Income Taxes - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100450 - Disclosure - Income Taxes - Schedule of Reconciliation of Statutory Federal Income Tax (Detail) link:calculationLink link:presentationLink link:definitionLink 100460 - Disclosure - Income Taxes - Schedule of Significant Components of Deferred Tax Assets and Liabilities (Detail) link:calculationLink link:presentationLink link:definitionLink 100470 - Disclosure - Net and Comprehensive Loss Per Share Attributable to Common Stockholders - Schedule of Computation of Basic and Diluted Net and Comprehensive Loss per Share (Detail) link:calculationLink link:presentationLink link:definitionLink 100480 - Disclosure - Net and Comprehensive Loss Per Share Attributable to Common Stockholders - Schedule of Weighted Average Common Stock Equivalents Excluded from Calculation of Diluted Net Loss per Share (Detail) link:calculationLink link:presentationLink link:definitionLink 100490 - Disclosure - Quarterly Results (unaudited) - Summary of Unaudited Quarterly Results (Detail) link:calculationLink link:presentationLink link:definitionLink 100500 - Disclosure - Quarterly Results (unaudited) - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100510 - Disclosure - Leases - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100520 - Disclosure - Leases - Summary of Lease Cost and Information Related to the Right-of-Use Assets and Operating Lease Liabilities (Detail) link:calculationLink link:presentationLink link:definitionLink 100530 - Disclosure - Leases - Schedule of Future Payments Related to Operating Leases Activities (Detail) link:calculationLink link:presentationLink link:definitionLink 100540 - Disclosure - Leases - Schedule of Future Payments Related to Operating Leases Activities (Detail)2 link:calculationLink link:presentationLink link:definitionLink 100550 - Disclosure - Employee Retirement Plan - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100560 - Disclosure - Employee Bonus Plan - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100570 - Disclosure - Employee Stock Purchase Plan - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100580 - Disclosure - License Agreement - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 100590 - Disclosure - Restructuring - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink