Entity Central Index Key Lessee operating lease liability payments due year three and thereafter. Cover [Abstract] Document Type Document Type Amendment Flag Amendment Flag Current Fiscal Year End Date Current Fiscal Year End Date Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Trading Symbol Trading Symbol Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Ex Transition Period Entity Ex Transition Period Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Common Stock, Shares Outstanding Entity Common Stock Shares Outstanding Entity Shell Company Entity Shell Company Entity Current Reporting Status Entity Current Reporting Status Entity File Number Entity File Number Entity Tax Identification Number Entity Tax Identification Number Entity Address, Address Line One Entity Address Address Line1 Entity Address, City or Town Entity Address City Or Town Entity Address, State or Province Entity Address State Or Province Entity Address, Postal Zip Code Entity Address Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Entity Interactive Data Current Entity Interactive Data Current Title of 12(b) Security Security12b Title Security Exchange Name Security Exchange Name Entity Incorporation, State or Country Code Entity Incorporation State Country Code Document Quarterly Report Document Quarterly Report Document Transition Report Document Transition Report Statement Of Financial Position [Abstract] Assets Assets [Abstract] Current assets: Assets Current [Abstract] Cash and cash equivalents Cash And Cash Equivalents At Carrying Value Prepaid research and development contracts Prepaid Expense Current Other current assets Other Assets Current Total current assets Assets Current Furniture and equipment, net Property Plant And Equipment Net Operating lease right-of-use assets, net Operating Lease Right Of Use Asset Deposits Deposits Assets Noncurrent Total assets Assets Liabilities and stockholders’ equity Liabilities And Stockholders Equity [Abstract] Current liabilities: Liabilities Current [Abstract] Accounts payable and accrued expenses Accounts Payable And Accrued Liabilities Current Current portion of operating lease liability Operating Lease Liability Current Total current liabilities Liabilities Current Operating lease liability, net of current portion Operating Lease Liability Noncurrent Total liabilities Liabilities Commitments and contingencies (Note 9) Commitments And Contingencies Stockholders’ equity: Stockholders Equity [Abstract] Common stock, $0.0001 par value per share; 300,000,000 shares authorized and 40,588,004 shares issued and outstanding at September 30, 2019 and December 31, 2018. Common Stock Value Additional paid-in capital Additional Paid In Capital Common Stock Accumulated deficit Retained Earnings Accumulated Deficit Total stockholders’ equity Stockholders Equity Total liabilities and stockholders’ equity Liabilities And Stockholders Equity Common stock, par value Common Stock Par Or Stated Value Per Share Common stock, shares authorized Common Stock Shares Authorized Common stock, shares issued Common Stock Shares Issued Common stock, shares outstanding Common Stock Shares Outstanding Restructuring expense benefit. Grant income. Income Statement [Abstract] License revenue, and other Revenue From Contract With Customer Excluding Assessed Tax Type of Revenue [Extensible List] Type Of Revenue Extensible List Operating expenses Operating Expenses [Abstract] Research and development Research And Development Expense General and administrative General And Administrative Expense Restructuring (benefit) expense Restructuring Expense Benefit Total operating expenses Operating Expenses (Loss) income from operations Operating Income Loss Grant income Grant Income Interest income Interest Income Expense Nonoperating Net Total other income Nonoperating Income Expense Net and comprehensive (loss) income Net Income Loss Net and comprehensive (loss) income per share Earnings Per Share [Abstract] Basic and diluted Earnings Per Share Basic And Diluted Weighted average number of common shares used in computing net and comprehensive (loss) income per share Weighted Average Number Of Shares Outstanding [Abstract] Basic Weighted Average Number Of Shares Outstanding Basic Diluted Weighted Average Number Of Diluted Shares Outstanding Cumulative effect of change in accounting principle in period of adoption. Statement Of Stockholders Equity [Abstract] Statement [Table] Statement [Table] Equity Components Statement Equity Components [Axis] Equity Component Equity Component [Domain] Common Stock [Member] Common Stock [Member] Additional Paid-In Capital [Member] Additional Paid In Capital [Member] Accumulated Deficit [Member] Retained Earnings [Member] Statement [Line Items] Statement [Line Items] Balance Balance, Shares Shares Outstanding Cumulative effect of change in accounting principle Cumulative Effect Of Change In Accounting Principle In Period Of Adoption Issuance of restricted stock Stock Issued During Period Value Restricted Stock Award Gross Issuance of restricted stock, Shares Stock Issued During Period Shares Restricted Stock Award Gross Issuance of common stock upon exercise of stock options Stock Issued During Period Value Stock Options Exercised Issuance of common stock upon exercise of stock options, Shares Stock Issued During Period Shares Stock Options Exercised Issuance of common stock,net of issuance costs Stock Issued During Period Value New Issues Issuance of common stock, net of issuance costs, Shares Stock Issued During Period Shares New Issues Forfeiture of restricted stock Stock Issued During Period Value Restricted Stock Award Forfeitures Forfeiture of restricted stock, Shares Stock Issued During Period Shares Restricted Stock Award Forfeited Stock-based compensation expense Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Net and comprehensive loss Balance Balance, Shares Payments of stock issuance cost Payments Of Stock Issuance Costs Increase decrease in prepaid research and development contracts. Statement Of Cash Flows [Abstract] Operating activities: Net Cash Provided By Used In Operating Activities [Abstract] Adjustments to reconcile net and comprehensive loss to net cash (used in) provided by operating activities: Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Depreciation Depreciation Stock-based compensation Share Based Compensation Changes in operating assets and liabilities: Increase Decrease In Operating Capital [Abstract] Prepaid research and development contracts Increase Decrease In Prepaid Research And Development Contracts Other current assets Increase Decrease In Other Current Assets Accounts payable and other current liabilities Increase Decrease In Accounts Payable And Other Operating Liabilities Net cash (used in) provided by operating activities Net Cash Provided By Used In Operating Activities Investing activities: Net Cash Provided By Used In Investing Activities [Abstract] Purchase of furniture and equipment Payments To Acquire Property Plant And Equipment Net cash used in investing activities Net Cash Provided By Used In Investing Activities Financing activities: Net Cash Provided By Used In Financing Activities [Abstract] Proceeds from exercise of stock options Proceeds From Stock Options Exercised Proceeds from issuance of common stock Proceeds From Issuance Of Common Stock Cash paid in connection with the sale of common stock Net cash provided by financing activities Net Cash Provided By Used In Financing Activities Net (decrease) increase in cash and cash equivalents Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect Cash and cash equivalents at beginning of year Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations Cash and cash equivalents, nine months ended Organization Consolidation And Presentation Of Financial Statements [Abstract] Nature of Organization and Operations Organization Consolidation And Presentation Of Financial Statements Disclosure [Text Block] Accounting Policies [Abstract] Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Payables And Accruals [Abstract] Accounts Payable and Accrued Expenses Accounts Payable And Accrued Liabilities Disclosure [Text Block] The entire disclosure for terms, amounts, nature of changes, rights and privileges, dividends, and other matters related to common stock. Preferred Stock and Common Stock [Abstract] Common Stock Common Stock [Text Block] Equity [Abstract] Preferred Stock Preferred Stock [Text Block] Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Stock-Based Compensation Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Income Tax Disclosure [Abstract] Income Taxes Income Tax Disclosure [Text Block] Net and Comprehensive (Loss) Income Per Share Earnings Per Share [Text Block] Leases [Abstract] Leases Lessee Operating Leases [Text Block] Disclosure of employee stock purchase plan. Employee Stock Purchase Plan Disclosure Of Employee Stock Purchase Plan [Text Block] License agreement. Revenue From Contract With Customer [Abstract] License Agreement License Agreement [Text Block] Restructuring And Related Activities [Abstract] Restructuring Restructuring And Related Activities Disclosure [Text Block] Subsequent Events [Abstract] Subsequent Event Subsequent Events [Text Block] Basis of Presentation Basis Of Accounting Policy Policy [Text Block] Segment Information Segment Reporting Policy Policy [Text Block] Use of Estimates Use Of Estimates Cash and Cash Equivalents Cash And Cash Equivalents Policy [Text Block] Revenue Recognition Revenue From Contract With Customer Policy [Text Block] Grant income. Grant Income Grant Income Policy [Text Block] Research and Development Research And Development Expense Policy Patents Intangible Assets Finite Lived Policy Costs Incurred To Renew Or Extend Income Taxes Income Tax Policy [Text Block] Net and Comprehensive (Loss) Income per Share Earnings Per Share Policy [Text Block] Stock-Based Compensation Share Based Compensation Option And Incentive Plans Policy Fair Value of Financial Instruments Fair Value Of Financial Instruments Policy Concentrations of Credit Risk and Off-Balance Sheet Risk Concentration Risk Credit Risk Comprehensive (Loss) Income Comprehensive Income Policy Policy [Text Block] Furniture and Equipment Property Plant And Equipment Policy [Text Block] Leases Lessee Leases Policy [Text Block] Recent Accounting Pronouncements New Accounting Pronouncements Policy Policy [Text Block] Schedule of Assets Measured on Recurring Basis Fair Value Assets Measured On Recurring Basis [Text Block] Schedule of Accounts Payable and Accrued Expenses Schedule Of Accounts Payable And Accrued Liabilities Table [Text Block] Summary of Stock Option Activity Schedule Of Share Based Compensation Stock Options Activity Table [Text Block] Summary of Recognized Compensation Cost Related to Employee and Non-employee Stock-Based Compensation Activity Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Stock Options Valuation Assumptions Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block] Schedule of Computation of Basic and Diluted Net (Loss) Income per Share Schedule Of Earnings Per Share Basic And Diluted Table [Text Block] Schedule of Weighted Average Common Stock Equivalents Excluded from Calculation of Basic and Diluted Net and Comprehensive (Loss) Income per Share Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block] Summary of Lease Cost and Information Related to the Right-of-Use Assets and Operating Lease Liabilities Lease Cost Table [Text Block] Schedule of Future Payments Related to Operating Leases Activities Lessee Operating Lease Liability Maturity Table [Text Block] Schedule Of Stock By Class [Table] Schedule Of Stock By Class [Table] Legal Entity Legal Entity [Axis] Entity Entity [Domain] Zeta Acquisition Corp. II. Zeta Acquisition Corp. II [Member] Zeta Acquisition Corp I I [Member] Sale of Stock Subsidiary Sale Of Stock [Axis] Sale of Stock Sale Of Stock Name Of Transaction [Domain] Private Placement [Member] Private Placement [Member] Statistical Measurement Range [Axis] Statistical Measurement Range [Member] Minimum [Member] Minimum [Member] Maximum [Member] Maximum [Member] Class Of Stock [Line Items] Class Of Stock [Line Items] Preferred stock, shares authorized Preferred Stock Shares Authorized Preferred stock, par value Preferred Stock Par Or Stated Value Per Share Capital stock conversion basis ratio. Capital stock conversion basis ratio Capital Stock Conversion Basis Ratio Warrants issuance term. Number of shares surrendered for cancellation Stock Repurchased And Retired During Period Shares Common stock sold in offering Common stock issued to private placement, price per share Shares Issued Price Per Share Net proceeds from issuance of common stock in private placement Proceeds From Issuance Of Private Placement Issuance of warrants term Warrants Issuance Term Number of warrants issued to purchase common stock Class Of Warrant Or Right Number Of Securities Called By Each Warrant Or Right Warrants issued to purchase common stock, exercise price Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1 Percentage of Interest owned in the combined enterprise Business Acquisition Percentage Of Voting Interests Acquired Summary of significant accounting policies. Summary of significant accounting policies. Summary Of Significant Accounting Policies [Table] Summary Of Significant Accounting Policies [Table] Adjustments for New Accounting Pronouncements Adjustments For New Accounting Pronouncements [Axis] Type of Adoption Type Of Adoption [Member] ASU 2018-07 [Member] Accounting Standards Update201807 [Member] Summary Of Significant Accounting Policies [Line Items] Summary Of Significant Accounting Policies [Line Items] Number of operating segment Number Of Operating Segments Uncertain tax positions Liability For Uncertain Tax Positions Current Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Measurement Frequency Fair Value By Measurement Frequency [Axis] Measurement Frequency Fair Value Measurement Frequency [Domain] Fair Value, Measurements, Recurring [Member] Fair Value Measurements Recurring [Member] Fair Value Hierarchy and NAV Fair Value By Fair Value Hierarchy Level [Axis] Fair Value Hierarchy and NAV Fair Value Measurements Fair Value Hierarchy [Domain] Level 1 [Member] Fair Value Inputs Level1 [Member] Level 2 [Member] Fair Value Inputs Level2 [Member] Level 3 [Member] Fair Value Inputs Level3 [Member] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Assets: Assets Fair Value Disclosure [Abstract] Cash and cash equivalents Cash And Cash Equivalents Fair Value Disclosure Total assets Assets Fair Value Disclosure Furniture and equipment estimated useful lives Property Plant And Equipment Useful Life One-time cumulative adjustment upon adoption Cumulative Effect Of New Accounting Principle In Period Of Adoption Accrued retention bonus current. Accrued project costs current. Accounts payable Accounts Payable Current Restructuring accrual (see Note 12) Restructuring Reserve Current Professional fees Accrued Professional Fees Current Accrued bonus Accrued Bonuses Current Accrued retention bonus Accrued Retention Bonus Current Accrued vacation Accrued Vacation Current Accrued project costs Accrued Project Costs Current Other Other Accrued Liabilities Current Total accounts payable and accrued expenses Dividends common stock declared or paid Dividends Common Stock Cash Class of warrant or right term. Class of warrant or right expiration date. Warrants outstanding Class Of Warrant Or Right Outstanding Warrants exercise price per share Warrants term Class Of Warrant Or Right Term Warrants expiration date Class Of Warrant Or Right Expiration Date Temporary Equity Disclosure [Abstract] Preferred stock, shares issued Preferred Stock Shares Issued Preferred stock, shares outstanding Preferred Stock Shares Outstanding Share based compensation arrangement by share based payment award number of additional shares authorized annual percentage. Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Plan Name Plan Name [Axis] Plan Name Plan Name [Domain] 2017 stock option and incentive plan. 2017 Stock Option and Incentive Plan [Member] Two Thousand Seventeen Stock Option And Incentive Plan [Member] Award Type Award Type [Axis] Award Type Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Stock Option [Member] Employee Stock Option [Member] Vesting Vesting [Axis] Vesting Vesting [Domain] One-year Anniversary [Member] Share Based Compensation Award Tranche One [Member] First Installment [Member] Share Based Compensation Award Tranche Two [Member] Second Installment [Member] Share Based Compensation Award Tranche Three [Member] Restricted Stock [Member] Restricted Stock [Member] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Common stock shares available for issuance Common Stock Capital Shares Reserved For Future Issuance Percentage applied to the outstanding shares as annual increase in number of shares authorized for issuance Share Based Compensation Arrangement By Share Based Payment Award Number Of Additional Shares Authorized Annual Percentage Shares issued for special retention grant. Share-based compensation arrangement by share-based payment award vesting date. Vesting period Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1 Vesting percentage Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage Term of options to be granted Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period Shares issued for special retention grant Shares Issued For Special Retention Grant Option, vesting date Share Based Compensation Arrangement By Share Based Payment Award Vesting Date Options to purchase common stock, granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross Shares, Outstanding at beginning balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number Shares, Granted Shares, Exercised Shares, Expired/cancelled Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period Shares, Outstanding at ending balance Shares, Expected to vest Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number Shares, Options exercisable Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number Weighted Average Exercise Price, Outstanding at beginning balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Weighted Average Exercise Price, Granted Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price Weighted Average Exercise Price, Exercised Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price Weighted Average Exercise Price, Expired/cancelled Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period Weighted Average Exercise Price Weighted Average Exercise Price, Outstanding at ending balance Weighted Average Exercise Price, Expected to vest Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price Weighted Average Exercise Price, Options exercisable Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price Weighted Average Remaining Contractual Term, Outstanding Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2 Weighted Average Remaining Contractual Term, Expected to vest Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1 Weighted Average Remaining Contractual Term, Options exercisable Sharebased Compensation Shares Authorized Under Stock Option Plans Exercise Price Range Exercisable Options Weighted Average Remaining Contractual Term2 Aggregate Intrinsic Value, Outstanding Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Aggregate Intrinsic Value, Expected to vest Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value Aggregate Intrinsic Value, Options exercisable Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1 Compensation expense Allocated Share Based Compensation Expense Unrecognized compensation cost related to stock options Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options Weighted average period expected to be recognized Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1 Disclosure Of Share Based Compensation Arrangements By Share Based Payment Award [Abstract] Disclosure Of Share Based Compensation Arrangements By Share Based Payment Award [Abstract] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Income Statement Location Income Statement Location [Axis] Income Statement Location Income Statement Location [Domain] Research and development [Member] Research And Development Expense [Member] General and administrative [Member] General And Administrative Expense [Member] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Stock-based compensation expense Weighted-average fair value of options granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value Expected term (years) Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1 Risk-free interest rate Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Expected volatility Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Expected dividend yield Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate Current income tax expense or benefit Current Income Tax Expense Benefit Deferred income tax expense or benefit Deferred Income Tax Expense Benefit Earnings per share. Earnings per share. Earnings Per Share [Table] Earnings Per Share [Table] Earnings Per Share [Line Items] Earnings Per Share [Line Items] Numerator: Net Income Loss Available To Common Stockholders Basic [Abstract] Net and comprehensive (loss) income attributable to common stockholders Net Income Loss Available To Common Stockholders Basic Denominator: Weighted Average Number Of Shares Outstanding Diluted Disclosure Items [Abstract] Denominator for basic EPS - weighted-average common shares Dilutive effect of shares Incremental Common Shares Attributable To Share Based Payment Arrangements Denominator for diluted EPS - adjusted weighted- average common shares Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Weighted Average [Member] Weighted Average [Member] Antidilutive Securities Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities, Name Antidilutive Securities Name [Domain] Warrants to Purchase Common Stock [Member] Warrant [Member] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Number of anti-dilutive securities excluded from computation of earnings per share Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Options to Purchase Common Stock [Member] Unvested Restricted Stock [Member] Total amount of anti-dilutive securities excluded from computation of earnings per share Lessee Lease Description [Table] Lessee Lease Description [Table] Lessee Lease Description [Line Items] Lessee Lease Description [Line Items] Lease arrangements renewal provisions Lessee Operating Lease Renewal Term Leases initial term Lessee Operating Lease Term Of Contract Lease other information. Cash paid for amounts included in measurement of operating lease liabilities. Weighted average remaining lease term and discount rate. Lease cost Lease Cost [Abstract] Average rent expense Operating Lease Cost Other information Lease Other Information [Abstract] Cash paid for amounts included in the measurement of operating lease liabilities Cash Paid For Amounts Included In Measurement Of Operating Lease Liabilities [Abstract] Operating cash flows from operating leases Operating Lease Payments The weighted average remaining lease term and discount rate Weighted Average Remaining Lease Term And Discount Rate [Abstract] Weighted-average remaining lease term - operating leases Operating Lease Weighted Average Remaining Lease Term1 Weighted-average discount rate - operating leases Operating Lease Weighted Average Discount Rate Percent Operating leases, 2019 Lessee Operating Lease Liability Payments Remainder Of Fiscal Year Operating leases, 2020 Lessee Operating Lease Liability Payments Due Year Two Operating leases, 2021 and thereafter Lessee Operating Lease Liability Payments Due Year Three And Thereafter Total Lease Payments Lessee Operating Lease Liability Payments Due Less interest Lessee Operating Lease Liability Undiscounted Excess Amount Present value of lease liabilities Operating Lease Liability Number of shares reserved for issuance annual increased percentage. Employee Stock Purchase Plan [Member] Employee Stock [Member] Maximum number of shares provided for issuance Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Authorized Percentage of annual increase in number of shares reserved for issuance Number Of Shares Reserved For Issuance Annual Increased Percentage Number of shares outstanding License Agreement. License agreement. License Agreement [Table] License Agreement [Table] Product and Service Product Or Service [Axis] Product and Service Products And Services [Domain] License [Member] License [Member] License Agreement [Line Items] License Agreement [Line Items] Cash received from license agreement Proceeds From License Fees Received License revenue Schedule Of Restructuring And Related Costs [Table] Schedule Of Restructuring And Related Costs [Table] Restructuring Type Restructuring Cost And Reserve [Axis] Type of Restructuring Type Of Restructuring [Domain] Workforce Reduction [Member] Employee Severance [Member] Balance Sheet Location Balance Sheet Location [Axis] Balance Sheet Location Balance Sheet Location [Domain] Accounts Payable and Accrued Expenses [Member] Accounts Payable And Accrued Liabilities [Member] Restructuring Cost And Reserve [Line Items] Restructuring Cost And Reserve [Line Items] Realignment plan, number of current workforce reduced Restructuring And Related Cost Number Of Positions Eliminated Realignment plan, number of workforce reduced, period percent Restructuring And Related Cost Number Of Positions Eliminated Period Percent Realignment plan, employee severance expense Severance Costs1 Cash payments against severance liability Payments For Restructuring Remaining liability related to severance Subsequent Event [Table] Subsequent Event [Table] Subsequent Event Type Subsequent Event Type [Axis] Subsequent Event Type Subsequent Event Type [Domain] Subsequent Event [Member] Subsequent Event [Member] Subsequent Event [Line Items] Subsequent Event [Line Items] Estimated employee related costs Restructuring And Related Cost Expected Cost Remaining1